Explore how you can contribute to each work package (WP) within EXPLAIN-IT and engage with a vibrant network of researchers across Europe.
Our research consortium offers a wide range of opportunities for collaboration, spanning data science, clinical research, exposome science, laboratory models, public engagement, and translational outcomes. View the opportunities for each work package below.
Sample Management & Harmonisation Coordination
• Develop and standardise collection, labeling, and storage protocols for breath, blood, and urine samples across ILD centers.
• Ensure biobanking integrity and regulatory compliance with ethical and GDPR standards.
• Oversee chain-of-custody documentation and coordinate with local site investigators for sample traceability.
Data Integration & Omics Analysis Support
• Integrate proteomic, metabolomic, and transcriptomic datasets into unified analytical structures.
• Design and refine multi-omics processing pipelines and metadata alignment strategies.
• Collaborate with computational biologists to ensure reproducibility, normalization accuracy, and secure data handling.
Airborne Exposome Data Analysis
• Process and interpret data from environmental samplers, including air quality and settled dust measurements.
• Model associations between environmental exposures and ILD clinical outcomes.
• Contribute to identifying exposure-specific molecular signatures through combined exposome–biomarker analyses.
Clinical Metadata & Data Curation
• Harmonize ILD clinical variables, including HRCT patterns, disease stage, and comorbidities.
• Establish standardized data dictionaries and ensure metadata completeness across sites.
• Maintain and update the unified ILD database for downstream statistical and omics analyses.
Quality Control & Data Validation
• Implement quality control protocols for omics, exposome, and clinical data.
• Verify consistency between laboratory outputs, sample inventories, and analytical records.
• Generate data validation reports and coordinate periodic QC audits for WP3B datasets.
Ethics & Data Governance Liaison
• Manage ethical approvals, informed consent documentation, and anonymization workflows.
• Supervise secure data exchange procedures and compliance with GDPR standards.
• Serve as point of contact for data governance matters and inter-institutional transfer agreements.
ILD Biomarker Validation Researcher
• Experimentally validate candidate biomarkers derived from multi-omics analyses in ILD patient samples.
• Perform laboratory assays, ELISA, and flow cytometry in collaboration with molecular and cellular pneumonology facilities.
• Interpret biomarker data to support translational research outputs and deliverable development.
ILD Clinical Data Coordinator
• Coordinate collection and entry of ILD clinical data including pulmonary function, HRCT metrics, and longitudinal follow-up.
•Liaise with participating centers to ensure data completeness and timely submission.
• Prepare curated clinical datasets for integrated analysis with exposome and biomarker information.
Biostatistical / Epidemiological Analysis
• Perform correlation, regression, and multivariate analyses linking exposome measures with biomarker and clinical data.
• Support the development of predictive models for ILD onset, progression, and exacerbations.
• Contribute to defining ILD-specific biomarker panels and validating their statistical robustness.
Pulmonary Function & Imaging Analysis
• Coordinate standardized acquisition and interpretation of spirometry, DLCO, and body plethysmography data.
• Lead HRCT scoring, quantitative image analysis, and integration with physiological measurements.
• Provide expertise for linking imaging and functional outcomes to molecular signatures.
Patient-Reported Outcomes (PRO) Data Liaison
• Manage implementation of patient-reported outcome measures (e.g., IPF-PROM) within ILD cohorts.
• Analyze associations between self-reported wellbeing indices and biological or exposome indicators.
• Support design of longitudinal frameworks to monitor quality of life and disease burden.
Research Assistance (ILD Data & Literature Support)
• Conduct literature reviews and evidence syntheses on ILD biomarkers and exposome interactions.
• Assist with data entry, reference management, and documentation for reports and manuscripts.
• Support day-to-day coordination of database updates, logistics, and internal communication.
Funding Strategy & Resource Development Officer
• Identify and track competitive funding schemes aligned with ILD exposome and biomarker research.
• Prepare pre-proposals, consortium inputs, and supporting documents for grant submissions.
• Coordinate with institutional funding offices to ensure strategic alignment and compliance.
• Develop sustainability plans securing long-term laboratory, data, and personnel resources beyond the CRC period.